University of Chicago

Yao B, Donoughe S, Michaux J, Munro E. Modulating RhoA effectors induces transitions to oscillatory and more wavelike RhoA dynamics in C. elegans zygotes. Mol Biol Cell. 2022 Feb 09; mbcE21110542.PMID: 35138935

Staddon MF, Munro EM, Banerjee S. Pulsatile contractions and pattern formation in excitable actomyosin cortex. PLoS Comput Biol. 2022 Mar; 18(3):e1009981.PMID: 35353813

Li Y, Munro E. (2021) Filament-guided filament assembly provides structural memory of filament alignment during cytokinesis. Dev Cell. 2021 Sep 1:S1534-5807(21)00668-7. doi: 10.1016/j.devcel.2021.08.009. Online ahead of print.PMID: 34480876

Weirich KL, Stam S, Munro E, Gardel ML. (2021) Actin bundle architecture and mechanics regulate myosin II force generation. Biophys J. 2021 May 18;120(10):1957-1970. doi: 10.1016/j.bpj.2021.03.026. Epub 2021 Mar 31.PMID: 33798565

Lenne PF, Munro E, Heemskerk I, Warmflash A, Bocanegra-Moreno L, Kishi K, Kicheva A, Long Y, Fruleux A, Boudaoud A, Saunders TE, Caldarelli P, Michaut A, Gros J, Maroudas-Sacks Y, Keren K, Hannezo E, Gartner ZJ, Stormo B, Gladfelter A, Rodrigues A, Shyer A, Minc N, Maître JL, Di Talia S, Khamaisi B, Sprinzak D, Tlili S. (2021) Roadmap for the multiscale coupling of biochemical and mechanical signals during development. Phys Biol. 2021 Apr 14;18(4):10.1088/1478-3975/abd0db. doi: 10.1088/1478-3975/abd0db.

Godard BG, Dumollard R, Munro E, Chenevert J, Hebras C, McDougall A, Heisenberg CP (2020) Apical Relaxation during Mitotic Rounding Promotes Tension-Oriented Cell Division. Dev Cell. 2020 Dec 21;55(6):695-706.e4. doi: 10.1016/j.devcel.2020.10.016. Epub 2020 Nov 17

Chen W, Hu Y, Lang CF, Brown JS, Schwabach S, Song X, Zhang Y, Munro E, Bennett K, Zhang D, Lee HC. (2020) The Dynamics of P Granule Liquid Droplets Are Regulated by the Caenorhabditis elegans Germline RNA Helicase GLH-1 via Its ATP Hydrolysis Cycle. Genetics 2020 Apr 3. pii: genetics.303052.2020. doi: 10.1534/genetics.120.303052. 

Cavanaugh KE, Staddon MF, Munro E, Banerjee S, Gardel ML. RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis. (2019) Dev Cell 2019 Dec 26. pii: S1534-5807(19)31023-8. doi: 10.1016/j.devcel.2019.12.002.

Hashimoto H, Munro E. Differential Expression of a Classic Cadherin Directs Tissue-Level Contractile Asymmetry during Neural Tube Closure (2019). Dev Cell. 2019 Oct 21;51(2):158-172.e4. doi: 10.1016/j.devcel.2019.10.001.

Staddon MF, Cavanaugh KE, Munro EM, Gardel ML, Banerjee S. (2019) Mechanosensitive Junction Remodeling Promotes Robust Epithelial Morphogenesis. Biophys J. 2019 Sep 28. pii: S0006-3495(19)30814-8. doi: 10.1016/j.bpj.2019.09.027.

Bailles A, Collinet C, Philippe JM, Lenne PF, Munro E, Lecuit T. (2019) Genetic induction and mechanochemical propagation of a morphogenetic wave. Nature. 2019 Aug;572(7770):467-473. doi: 10.1038/s41586-019-1492-9.

Michaux JB, Robin FB,  McFadden WM, Munro EM. (2018) Excitable RhoA dynamics drive pulsed contractions in the early C. elegans embryo. J Cell Biol. 2018 Oct 1. doi: 10.1083/jcb.201806161. [Epub ahead of print]

Wu Y, Han B, Li Y, Munro E, Odde DJ, Griffin EE. (2018). Rapid diffusion-state switching underlies stable cytoplasmic gradients in the Caenorhabditis elegans zygote. Proc Natl Acad Sci U S A. 2018 Jul 24. pii: 201722162. doi: 10.1073/pnas.1722162115.

Hashimoto H, Munro E. (2018). Dynamic interplay of cell fate, polarity and force generation in ascidian embryos Curr Opin Genet Dev., 51:67-77, doi: 10.1016/j.gde.2018.06.013.

McFadden WM, McCall PM, Gardel ML, Munro EM. (2017). Filament turnover tunes both force generation and dissipation to control long-range flows in a model actomyosin cortex PLoS Comput Biol., 13(12), doi: 10.1371/journal.pcbi.1005811.

Lang CF, Munro E. (2017). The PAR proteins: from molecular circuits to dynamic self-stabilizing cell polarity. Development, 144(19):3405-3416. doi: 10.1242/dev.139063.

Munro E. (2017). Protein Clustering Shapes Polarity Protein Gradients. Developmental Cell, 42(4), 309-311. http://dx.doi.org/10.1016/j.devcel.2017.08.006

Sailer A, Anneken A, Li Y, Lee S, & Munro E. (2015). Dynamic Opposition of Clustered Proteins Stabilizes Cortical Polarity in the C. elegans Zygote. Developmental Cell, 35(1), 131–142. http://doi.org/10.1016/j.devcel.2015.09.006

Munjal A, Philippe JM, Munro E, Lecuit T. (2015). A self-organized biomechanical network drives shape changes during tissue morphogenesis. Nature, 524(7565):351-5. doi: 10.1038/nature14603.

Stam S, Alberts J, Gardel ML, Munro E. (2015). Isoforms Confer Characteristic Force Generation and Mechanosensation by Myosin II Filaments. Biophys J.,108(8):1997-2006. doi: 10.1016/j.bpj.2015.03.030.

Hashimoto H, Robin FB, Sherrard KM, & Munro EM (2015). Sequential contraction and exchange of apical junctions drives zippering and neural tube closure in a simple chordate. Developmental Cell, 32(2), 241–255. http://doi.org/10.1016/j.devcel.2014.12.017

Markova O, Alberts J, Munro E, Lenne PF. (2014). Clustering of low-valence particles: structure and kinetics. Phys Rev E Stat Nonlin Soft Matter Phys., 90(2):022301.

Robin FB, McFadden WM, Yao B, & Munro EM (2014). Single-molecule analysis of cell surface dynamics in Caenorhabditis elegans embryos. Nature Methods, 11(6), 677–682. http://doi.org/10.1038/nmeth.2928

Kim T, Gardel ML, Munro E. (2014). Determinants of fluidlike behavior and effective viscosity in cross-linked actin networks. Biophys J., 106(3):526-34. doi: 10.1016/j.bpj.2013.12.031.

Markova O, Alberts J, Munro E, Lenne PF. (2012). Bond flexibility and low valence promote finite clusters of self-aggregating particles. Phys Rev Lett., 109(7):078101.

Dawes AT, Munro EM. (2011). PAR-3 oligomerization may provide an actin-independent mechanism to maintain distinct par protein domains in the early Caenorhabditis elegans embryo. Biophys J., 101(6):1412-22. doi: 10.1016/j.bpj.2011.07.030.

Horne-Badovinac S, Munro E. (2011). Tubular transformations. Science., 333(6040):294-5. doi: 10.1126/science.1209687.

Lecuit T, Lenne PF, Munro E. (2011). Force generation, transmission, and integration during cell and tissue morphogenesis. Annu Rev Cell Dev Biol., 27:157-84. doi: 10.1146/annurev-cellbio-100109-104027.

Center for Cell Dynamics at University of Washington

Hoyos E, Kim K, Milloz J, Barkoulas M, Pénigault JB, Munro E, Félix MA. (2011). Quantitative variation in autocrine signaling and pathway crosstalk in the Caenorhabditis vulval network. Curr Biol., 21(7):527-38. doi: 10.1016/j.cub.2011.02.040.

Sherrard K, Robin F, Lemaire P, Munro E. (2010). Sequential activation of apical and basolateral contractility drives ascidian endoderm invagination. Curr Biol., 20(17):1499-510. doi: 10.1016/j.cub.2010.06.075.

Munro E, Bowerman B. (2009). Cellular symmetry breaking during Caenorhabditis elegans development. Cold Spring Harb Perspect Biol., 1(4):a003400. doi: 10.1101/cshperspect.a003400.

Bellaïche Y, Munro E. (2009). Pushing the frontiers of development. Development., 136(2):173-7. doi: 10.1242/dev.028407.

Shi W, Peyrot SM, Munro E, Levine M. (2009). FGF3 in the floor plate directs notochord convergent extension in the Ciona tadpole. Development., 136(1):23-8. doi: 10.1242/dev.029157.

Gallo CM, Munro E, Rasoloson D, Merritt C, Seydoux G. (2008). Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos. Dev Biol., 323(1):76-87. doi: 10.1016/j.ydbio.2008.07.008.

Baruni JK, Munro EM, von Dassow G. (2008). Cytokinetic furrowing in toroidal, binucleate and anucleate cells in C. elegans embryos. J Cell Sci., 121(Pt 3):306-16. doi: 10.1242/jcs.022897.

Werner M, Munro E, Glotzer M. (2007). Astral signals spatially bias cortical myosin recruitment to break symmetry and promote cytokinesis. Curr Biol., 17(15):1286-97.

Munro E. (2007). Asymmetric cell division: a CAB driver for spindle movements. Curr Biol., 17(16):R639-41.

Munro E. (2007). The microtubules dance and the spindle poles swing. Cell., 129(3):457-8.

Munro E, Robin F, Lemaire P. (2006). Cellular morphogenesis in ascidians: how to shape a simple tadpole. Curr Opin Genet Dev., 16(4):399-405.

Willis JH, Munro E, Lyczak R, Bowerman B. (2006). Conditional dominant mutations in the Caenorhabditis elegans gene act-2 identify cytoplasmic and muscle roles for a redundant actin isoform. Mol Biol Cell., 17(3):1051-64.

Munro EM. (2006). PAR proteins and the cytoskeleton: a marriage of equals. Curr Opin Cell Biol., 18(1):86-94. 

Jiang D, Munro EM, Smith WC. (2005). Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells. Curr Biol., 15(1):79-85.

Postdoctoral Fellow (Fred Hutchinson Cancer Research Center)

Munro E, Nance J, Priess JR. (2004). Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo. Dev Cell., 7(3):413-24.

Nance J, Munro EM, Priess JR. (2003). C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation. Development., 130(22):5339-50.

Graduate School (University of Washington)

Meir E, Munro EM, Odell GM, Von Dassow G. (2002). Ingeneue: a versatile tool for reconstituting genetic networks, with examples from the segment polarity network. J Exp Zool., 294(3):216-51.

Meir E, von Dassow G, Munro E, Odell GM. (2002). Robustness, flexibility, and the role of lateral inhibition in the neurogenic network. Curr Biol., 12(10):778-86.

Munro EM, Odell GM. (2002). Polarized basolateral cell motility underlies invagination and convergent extension of the ascidian notochord. Development., 129(1):13-24.

Munro EM, Odell G. (2002). Morphogenetic pattern formation during ascidian notochord formation is regulative and highly robust. Development., 129(1):1-12.

von Dassow G, Meir E, Munro EM, Odell GM. (2000). The segment polarity network is a robust developmental module. Nature., 406(6792):188-92.

von Dassow G, Munro E. (1999). Modularity in animal development and evolution: elements of a conceptual framework for EvoDevo. J Exp Zool., 285(4):307-25.

Other

Munro E, Shupe L, Fetz E. (1994). Integration and differentiation in dynamic recurrent neural networks. Neural Computation, Vol. 6, No. 3, Pages 405-419.