Welcome to the Munro Lab
We seek to understand how embryonic cells organize morphogenetic activities in space and time. How do they organize force production in space and time? How they harness these forces to polarize, divide, move and change shape? How do groups of cells work together to shape embryonic tissues?, and how do these cell and tissue-level behaviors emerge from the dynamic interplay of biochemical signaling, cytoskeletal dynamics and cell mechanics. To address these questions, we combine traditional approaches from molecular genetics and cell biology with quantitative microscopy and mathematical modeling.
- See our new preprint on biorxv on how actin filaments are aligned during cytokinesis April 14, 2020
- See our new research article in Developmental Cell on how differential expression of cadherins directs tissue zippering October 28, 2019
- See our new article in JCB on the dynamic control of pulsed contractions in the C. elegans embryo October 1, 2018
- See our new preprint on biorxiv on the role of Cadherins in patterning Myosin activity during neural tube closure in ascidians September 26, 2018
- See our new review article in Current Opinion in Genetics & Development about the mechanics of ascidian embryonic development July 17, 2018